SPLENDA® Brand Sweetener (sucralose) was discovered in 1976, and for the next 20 years was subjected to one of the most extensive and thorough safety testing programs ever conducted on a food additive. The peer-reviewed journal publications below provide a synopsis of the literature. An in-depth review of the research conducted is provided in the publication "An Overview of the Safety of Sucralose."
Grotz VL, Munro IC. An overview of the safety of sucralose. Regul Toxicol Pharmacol 2009;55:1-5.
Grice HC, Goldsmith LA. Sucralose – An overview of the toxicity data. Food Chem Toxicol. 2000;38 Suppl 2:S1-6.
Read answers to commonly asked questions about SPLENDA® Sweetener Products, usage, effect of sucralose on blood glucose levels, and comparison with other sweeteners.