Safety Studies

SPLENDA^® Brand Sweetener (sucralose) was discovered in 1976, and for the next 20 years was subjected to one of the most extensive and thorough safety testing programs ever conducted on a food additive. The peer-reviewed journal publications below provide a synopsis of the literature. An in-depth review of the research conducted is provided in the publication "An Overview of the Safety of Sucralose."

Sucralose: A Scientific and Safety Review

Grotz VL, Munro IC. An overview of the safety of sucralose. Regul Toxicol Pharmacol 2009;55:1-5.

Grice HC, Goldsmith LA. Sucralose – An overview of the toxicity data. Food Chem Toxicol. 2000;38 Suppl 2:S1-6.

FDA 21CFR101.80.

Know The Facts

Read answers to commonly asked questions about SPLENDA^® Sweetener Products, usage, effect of sucralose on blood glucose levels, and comparison with other sweeteners.

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Questions or comments? Call the toll-free SPLENDA^® Healthcare Professional line at 1-866-948-6883 or go to Customer Service.
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