Safety Studies

An Overview Of The Safety Of Sucralose

Grotz VL, Munroe IC. Regulatory Toxicology and Pharmocology. 2009;55:1-5

A review of the extensive body of evidence that supports the safety of sucralose. The results of an independent review of a recent study investigating the safety of a sucralose-mixture retail product, SPLENDA^® No Calorie Sweetener, Granulated, are also discussed. Covers:

• Physiochemical properties and pharmacokinetics

• Acute exposure

• Long-term safety

• Clinical studies

• Estimated daily intake and sucralose mixtures